An Evaluation of Replacing Fish Meal with Fermented Soybean Meal in Diet of Hybrid Snakehead (Channa argus × Channa maculata): Growth, Nutrient Utilization, Serum Biochemical Indices, Intestinal Histology, and Microbial Community

The present study investigated the effect of fish meal (FM) replacement with fermented soybean (FSM) on growth performance, nutrient utilization, serum biochemical indices, intestinal histology, and microbial community hybrid snakehead. Five isonitrogenous diets were formulated FSM inclusion to decrease dietary FM from 350 g/kg (the control diet) 300, 250, 200, 150 g/kg, referring CON, FM-30, FM-25, FM-20, FM-15, respectively, then fed snakehead initial body weight 6.49 ± 0.03 g for 60 days. group showed best a gain rate (WGR) 417.0% feed conversion ratio (FCR) 0.84, but WGR in FM-15 groups was decreased by 26.25%, 40.60%, 42.23% FCR increased 0.24, 0.45, when compared those CON ( id="M2"> P < 0.05 ). apparent digestibility coefficients dry matter crude protein, protein efficiency retention, total cholesterol content, muscle thickness FM-20 villus height all significantly lower than id="M3"> Intestinal microbiota analysis indicated that main microorganisms included Proteobacteria, Firmicutes, Actinobacteria. At genus level, Plesiomonas dominant highest relative abundance group. In summary, diet containing FM, can successfully replace 50 without negative effects health juvenile.